In this review, the germination mechanism, heterogeneity, and influencing factors have been outlined along with knowledge gaps. This work aimed to critically review the current state of knowledge on Bacillus spore germination at a moderate HP of 50–300 MPa. Therefore, there is a need to elucidate the mechanisms of HP-mediated germination. The successful and safe implementation of the germination-inactivation strategy, however, depends on the germination of all spores. However, pressure-mediated spore germination is extremely heterogeneous as some spores germinate rapidly, while others exhibit slow germination or do not undergo germination at all. Among those, isostatic high pressure (HP) has gained increasing attention due to its potential applications in industrial processes. Different stimuli are reported to trigger germination. This germination-inactivation strategy allows better maintenance of important food quality attributes. Targeted germination can aid in decreasing the resistance of spores and allow the application of milder inactivation procedures. The inhibition and induction of germination have critical applications in the food industry. As spore germination is critical for the loss of resistance, outgrowth, and development of pathogenicity and spoilage potential, the germination pathway has piqued the interest of the scientific community. Bacterial spores may return to their vegetative state through a process called germination. These spores can survive adverse environmental conditions in nature, as well as decontamination processes in the food and related industries. Continued abuse of our services will cause your IP address to be blocked indefinitely.Spore-forming bacteria are resistant to stress conditions owing to their ability to form highly resistant dormant spores. Please fill out the CAPTCHA below and then click the button to indicate that you agree to these terms. If you wish to be unblocked, you must agree that you will take immediate steps to rectify this issue. If you do not understand what is causing this behavior, please contact us here. If you promise to stop (by clicking the Agree button below), we'll unblock your connection for now, but we will immediately re-block it if we detect additional bad behavior. Overusing our search engine with a very large number of searches in a very short amount of time.Using a badly configured (or badly written) browser add-on for blocking content.Running a "scraper" or "downloader" program that either does not identify itself or uses fake headers to elude detection.Using a script or add-on that scans GameFAQs for box and screen images (such as an emulator front-end), while overloading our search engine.There is no official GameFAQs app, and we do not support nor have any contact with the makers of these unofficial apps.
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